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A novel pre-clinical strategy to deliver antimicrobial doses of inhaled nitric oxide
Effective treatment of respiratory infections continues to be a major challenge. In high doses (≥160 ppm), inhaled Nitric Oxide (iNO) has been shown to act as a broad-spectrum antimicrobial agent, including its efficacy in vitro for coronavirus family. However, the safety of prolonged in vivo implem...
Autores principales: | Michaelsen, Vinicius S., Ribeiro, Rafaela V. P., Brambate, Edson, Ali, Aadil, Wang, Aizhou, Pires, Layla, Kawashima, Mitsuaki, Zhang, Yu, Gazzalle, Anajara, Keshavjee, Shaf, Del Sorbo, Lorenzo, Cypel, Marcelo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513841/ https://www.ncbi.nlm.nih.gov/pubmed/34644318 http://dx.doi.org/10.1371/journal.pone.0258368 |
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