The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation

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Viral proteins localize within subcellular compartments to subvert host machinery and promote pathogenesis. To study SARS-CoV-2 biology, we generated an atlas of 2422 human proteins vicinal to 17 SARS-CoV-2 viral proteins using proximity proteomics. This identified viral proteins at specific intrace...

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Detalles Bibliográficos
Autores principales: Meyers, Jordan M., Ramanathan, Muthukumar, Shanderson, Ronald L., Beck, Aimee, Donohue, Laura, Ferguson, Ian, Guo, Margaret G., Rao, Deepti S., Miao, Weili, Reynolds, David, Yang, Xue, Zhao, Yang, Yang, Yen-Yu, Blish, Catherine, Wang, Yinsheng, Khavari, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513853/
https://www.ncbi.nlm.nih.gov/pubmed/34597346
http://dx.doi.org/10.1371/journal.ppat.1009412
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