Cargando…

Nascent chain dynamics and ribosome interactions within folded ribosome–nascent chain complexes observed by NMR spectroscopy

The folding of many proteins can begin during biosynthesis on the ribosome and can be modulated by the ribosome itself. Such perturbations are generally believed to be mediated through interactions between the nascent chain and the ribosome surface, but despite recent progress in characterising inte...

Descripción completa

Detalles Bibliográficos
Autores principales:	Burridge, Charles, Waudby, Christopher A., Włodarski, Tomasz, Cassaignau, Anaïs M. E., Cabrita, Lisa D., Christodoulou, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8513902/ https://www.ncbi.nlm.nih.gov/pubmed/34745542 http://dx.doi.org/10.1039/d1sc04313g

Ejemplares similares

Increasing the sensitivity of NMR diffusion measurements by paramagnetic longitudinal relaxation enhancement, with application to ribosome–nascent chain complexes
por: Chan, Sammy H. S., et al.
Publicado: (2015)

Common sequence motifs of nascent chains engage the ribosome surface and trigger factor
por: Deckert, Annika, et al.
Publicado: (2021)

Interactions between nascent proteins and the ribosome surface inhibit co-translational folding
por: Cassaignau, Anaïs M. E., et al.
Publicado: (2021)

A structural ensemble of a ribosome-nascent chain complex during co-translational protein folding
por: Cabrita, Lisa D., et al.
Publicado: (2016)

The ribosome stabilizes partially folded intermediates of a nascent multi-domain protein
por: Chan, Sammy H. S., et al.
Publicado: (2022)

Nascent chains can form co-translational folding intermediates that promote post-translational folding outcomes in a disease-causing protein
por: Plessa, Elena, et al.
Publicado: (2021)

Protein folding on the ribosome studied using NMR spectroscopy
por: Waudby, Christopher A., et al.
Publicado: (2013)

Ribosomes have a NAC for nascent chain processing
por: Short, Ben
Publicado: (2015)

Modulating co-translational protein folding by rational design and ribosome engineering
por: Ahn, Minkoo, et al.
Publicado: (2022)

Nuclear translation visualized by ribosome-bound nascent chain puromycylation
por: David, Alexandre, et al.
Publicado: (2012)

Author Correction: Modulating co-translational protein folding by rational design and ribosome engineering
por: Ahn, Minkoo, et al.
Publicado: (2022)

Nascent SecM Chain Outside the Ribosome Reinforces Translation Arrest
por: Yang, Zhuohao, et al.
Publicado: (2015)

Gradual compaction of the nascent peptide during cotranslational folding on the ribosome
por: Liutkute, Marija, et al.
Publicado: (2020)

Immunoprecipitation of Reporter Nascent Chains from Active Ribosomes to Study Translation Efficiency
por: Cacioppo, Roberta, et al.
Publicado: (2023)

Folding stabilities of ribosome-bound nascent polypeptides probed by mass spectrometry
por: Tan, Ruiyue, et al.
Publicado: (2023)

NAC covers ribosome-associated nascent chains thereby forming a protective environment for regions of nascent chains just emerging from the peptidyl transferase center
Publicado: (1995)

Prefoldin–Nascent Chain Complexes in the Folding of Cytoskeletal Proteins
por: Hansen, William J., et al.
Publicado: (1999)

Nascent polypeptide chains exit the ribosome in the same relative position in both eucaryotes and procaryotes
Publicado: (1983)

Identification of a Novel Stage of Ribosome/Nascent Chain Association with the Endoplasmic Reticulum Membrane
por: Murphy, Edwin C., et al.
Publicado: (1997)

Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain
por: Lintner, Nathanael G., et al.
Publicado: (2017)

Elongation inhibitors do not prevent the release of puromycylated nascent polypeptide chains from ribosomes
por: Hobson, Benjamin D, et al.
Publicado: (2020)

Nascent SecM chain interacts with outer ribosomal surface to stabilize translation arrest
por: Muta, Mikihisa, et al.
Publicado: (2020)

The ribosome-associated complex RAC serves in a relay that directs nascent chains to Ssb
por: Zhang, Ying, et al.
Publicado: (2020)

Shaping the Nascent Ribosome: AAA-ATPases in Eukaryotic Ribosome Biogenesis
por: Prattes, Michael, et al.
Publicado: (2019)

Membrane-bound ribosomes of myeloma cells. III. The role of the messenger RNA and the nascent polypeptide chain in the binding of ribosomes to membranes
Publicado: (1975)

Multivalent contacts of the Hsp70 Ssb contribute to its architecture on ribosomes and nascent chain interaction
por: Hanebuth, Marie A., et al.
Publicado: (2016)

Correction: Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain
por: Lintner, Nathanael G., et al.
Publicado: (2018)

MifM-instructed translation arrest involves nascent chain interactions with the exterior as well as the interior of the ribosome
por: Fujiwara, Keigo, et al.
Publicado: (2018)

Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule
por: Li, Wenfei, et al.
Publicado: (2019)

Coordination of -1 programmed ribosomal frameshifting by transcript and nascent chain features revealed by deep mutational scanning
por: Carmody, Patrick J, et al.
Publicado: (2021)

Ribosome selectivity and nascent chain context in modulating the incorporation of fluorescent non-canonical amino acid into proteins
por: Thommen, Michael, et al.
Publicado: (2022)

The Rqc2/Tae2 subunit of the ribosome-associated quality control (RQC) complex marks ribosome-stalled nascent polypeptide chains for aggregation
por: Yonashiro, Ryo, et al.
Publicado: (2016)

Nature and Regulation of Protein Folding on the Ribosome
por: Waudby, Christopher A., et al.
Publicado: (2019)

Defining the Specificity of Cotranslationally Acting Chaperones by Systematic Analysis of mRNAs Associated with Ribosome-Nascent Chain Complexes
por: del Alamo, Marta, et al.
Publicado: (2011)

Vms1/Ankzf1 peptidyl-tRNA hydrolase releases nascent chains from stalled ribosomes
por: Verma, Rati, et al.
Publicado: (2018)

Critical 23S rRNA interactions for macrolide-dependent ribosome stalling on the ErmCL nascent peptide chain
por: Koch, Miriam, et al.
Publicado: (2017)

Capturing Membrane Protein Ribosome Nascent Chain Complexes in a Native-like Environment for Co-translational Studies
por: Pellowe, Grant A., et al.
Publicado: (2020)

MITRAC15/COA1 promotes mitochondrial translation in a ND2 ribosome–nascent chain complex
por: Wang, Cong, et al.
Publicado: (2019)

The dynamic architecture of Map1- and NatB-ribosome complexes coordinates the sequential modifications of nascent polypeptide chains
por: Knorr, Alexandra G., et al.
Publicado: (2023)

Co-translational capturing of nascent ribosomal proteins by their dedicated chaperones
por: Pausch, Patrick, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_ph98l6pgsl205v1o4b3q0ug15a