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Making Connections: Integrative Signaling Mechanisms Coordinate DNA Break Repair in Chromatin

DNA double-strand breaks (DSBs) are hazardous to genome integrity and can promote mutations and disease if not handled correctly. Cells respond to these dangers by engaging DNA damage response (DDR) pathways that are able to identify DNA breaks within chromatin leading ultimately to their repair. Th...

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Detalles Bibliográficos
Autores principales: Sanchez, Anthony, Lee, Doohyung, Kim, Dae In, Miller, Kyle M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514019/
https://www.ncbi.nlm.nih.gov/pubmed/34659365
http://dx.doi.org/10.3389/fgene.2021.747734