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Making Connections: Integrative Signaling Mechanisms Coordinate DNA Break Repair in Chromatin
DNA double-strand breaks (DSBs) are hazardous to genome integrity and can promote mutations and disease if not handled correctly. Cells respond to these dangers by engaging DNA damage response (DDR) pathways that are able to identify DNA breaks within chromatin leading ultimately to their repair. Th...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514019/ https://www.ncbi.nlm.nih.gov/pubmed/34659365 http://dx.doi.org/10.3389/fgene.2021.747734 |