GLUT4-overexpressing engineered muscle constructs as a therapeutic platform to normalize glycemia in diabetic mice

Skeletal muscle insulin resistance is a main defect in type 2 diabetes (T2D), which is associated with impaired function and content of glucose transporter type 4 (GLUT4). GLUT4 overexpression in skeletal muscle tissue can improve glucose homeostasis. Therefore, we created an engineered muscle const...

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Detalles Bibliográficos
Autores principales: Beckerman, Margarita, Harel, Chava, Michael, Inbal, Klip, Amira, Bilan, Philip J., Gallagher, Emily J., LeRoith, Derek, Lewis, Eli C., Karnieli, Eddy, Levenberg, Shulamit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514095/
https://www.ncbi.nlm.nih.gov/pubmed/34644106
http://dx.doi.org/10.1126/sciadv.abg3947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514095/
https://www.ncbi.nlm.nih.gov/pubmed/34644106
http://dx.doi.org/10.1126/sciadv.abg3947

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