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Ciliary protein Kif7 regulates Gli and Ezh2 for initiating the neuronal differentiation of enteric neural crest cells during development

Gastrointestinal motility disorders occur frequently in patients with ciliopathy, but the underlying genetic link is unclear. The ciliary protein Kif7 can positively or negatively regulate Hedgehog signaling in different cellular contexts. Mice with neural crest cell (NCC)–specific Kif7 deficiency s...

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Detalles Bibliográficos
Autores principales:	Lai, Frank Pui-Ling, Li, Zhixin, Zhou, Tingwen, Leung, Adrian On Wah, Lau, Sin-Ting, Lui, Kathy Nga-Chu, Wong, William Yu-Ming, Sham, Pak-Chung, Hui, Chi-Chung, Ngan, Elly Sau-Wai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2021
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514102/ https://www.ncbi.nlm.nih.gov/pubmed/34644112 http://dx.doi.org/10.1126/sciadv.abf7472

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