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Comparison of the Effects of Beclomethasone Dipropionate and Budesonide in the Treatment of Children with Mild, Persistent Asthma

Objective To compare the mean change in peak expiratory flow values in children receiving inhaled beclomethasone dipropionate versus inhaled budesonide in the treatment of mild persistent asthma. Method The medical records of 60 patients from the outpatient department (OPD)/emergency room (ER), Natio...

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Autores principales: Bukhari, Ibrahim, Ashfaq, Muhammad, Nisa, Bader-u-, Ahmed, Aijaz, Waseem, Hira, Yasir, Mehrunnisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514125/
https://www.ncbi.nlm.nih.gov/pubmed/34660132
http://dx.doi.org/10.7759/cureus.17943
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author Bukhari, Ibrahim
Ashfaq, Muhammad
Nisa, Bader-u-
Ahmed, Aijaz
Waseem, Hira
Yasir, Mehrunnisa
author_facet Bukhari, Ibrahim
Ashfaq, Muhammad
Nisa, Bader-u-
Ahmed, Aijaz
Waseem, Hira
Yasir, Mehrunnisa
author_sort Bukhari, Ibrahim
collection PubMed
description Objective To compare the mean change in peak expiratory flow values in children receiving inhaled beclomethasone dipropionate versus inhaled budesonide in the treatment of mild persistent asthma. Method The medical records of 60 patients from the outpatient department (OPD)/emergency room (ER), National Institute of Child Health, Karachi, who received beclomethasone dipropionate (BDP) 200 µg one puff and budesonide (BUD) 200 µg one puff twice a day for treatment of mild persistent asthma from March 10, 2020, to August 10, 2020, were explored. Results The mean age of children was 10.56 ± 3.01 years in the BUD group and 10.05 ± 3.54 years in the BDP group. The mean change in peak expiratory flow % in the BUD group was 15.69 ± 3.59%, and in the BDP group, it was 13.59 ± 4.26% (P-value=0.04) Conclusion BDP and budesonide (BUD) were both found to be effective for the treatment of mild persistent asthma in children. However, we found that BUD had better efficacy compared to BDP.
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spelling pubmed-85141252021-10-15 Comparison of the Effects of Beclomethasone Dipropionate and Budesonide in the Treatment of Children with Mild, Persistent Asthma Bukhari, Ibrahim Ashfaq, Muhammad Nisa, Bader-u- Ahmed, Aijaz Waseem, Hira Yasir, Mehrunnisa Cureus Pediatrics Objective To compare the mean change in peak expiratory flow values in children receiving inhaled beclomethasone dipropionate versus inhaled budesonide in the treatment of mild persistent asthma. Method The medical records of 60 patients from the outpatient department (OPD)/emergency room (ER), National Institute of Child Health, Karachi, who received beclomethasone dipropionate (BDP) 200 µg one puff and budesonide (BUD) 200 µg one puff twice a day for treatment of mild persistent asthma from March 10, 2020, to August 10, 2020, were explored. Results The mean age of children was 10.56 ± 3.01 years in the BUD group and 10.05 ± 3.54 years in the BDP group. The mean change in peak expiratory flow % in the BUD group was 15.69 ± 3.59%, and in the BDP group, it was 13.59 ± 4.26% (P-value=0.04) Conclusion BDP and budesonide (BUD) were both found to be effective for the treatment of mild persistent asthma in children. However, we found that BUD had better efficacy compared to BDP. Cureus 2021-09-13 /pmc/articles/PMC8514125/ /pubmed/34660132 http://dx.doi.org/10.7759/cureus.17943 Text en Copyright © 2021, Bukhari et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pediatrics
Bukhari, Ibrahim
Ashfaq, Muhammad
Nisa, Bader-u-
Ahmed, Aijaz
Waseem, Hira
Yasir, Mehrunnisa
Comparison of the Effects of Beclomethasone Dipropionate and Budesonide in the Treatment of Children with Mild, Persistent Asthma
title Comparison of the Effects of Beclomethasone Dipropionate and Budesonide in the Treatment of Children with Mild, Persistent Asthma
title_full Comparison of the Effects of Beclomethasone Dipropionate and Budesonide in the Treatment of Children with Mild, Persistent Asthma
title_fullStr Comparison of the Effects of Beclomethasone Dipropionate and Budesonide in the Treatment of Children with Mild, Persistent Asthma
title_full_unstemmed Comparison of the Effects of Beclomethasone Dipropionate and Budesonide in the Treatment of Children with Mild, Persistent Asthma
title_short Comparison of the Effects of Beclomethasone Dipropionate and Budesonide in the Treatment of Children with Mild, Persistent Asthma
title_sort comparison of the effects of beclomethasone dipropionate and budesonide in the treatment of children with mild, persistent asthma
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514125/
https://www.ncbi.nlm.nih.gov/pubmed/34660132
http://dx.doi.org/10.7759/cureus.17943
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