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Chrysophanol Relieves Cisplatin-Induced Nephrotoxicity via Concomitant Inhibition of Oxidative Stress, Apoptosis, and Inflammation

Cisplatin (CDDP) is one of the most frequently prescribed chemotherapy medications. However, its nephrotoxicity which often leads to acute kidney injury (AKI), greatly limits its clinical application. Chrysophanol (CHR), a mainly active anthraquinone ingredient, possesses various biological and phar...

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Detalles Bibliográficos
Autores principales: Ma, Siqing, Xu, Heng, Huang, Weihua, Gao, Yongchao, Zhou, Honghao, Li, Xiong, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514135/
https://www.ncbi.nlm.nih.gov/pubmed/34658905
http://dx.doi.org/10.3389/fphys.2021.706359