Cargando…

SCAMP3 is a mutant EGFR phosphorylation target and a tumor suppressor in lung adenocarcinoma

Mutations in the epidermal growth factor receptor (EGFR) tyrosine kinase domain constitutively activate EGFR resulting in lung tumorigenesis. Activated EGFR modulates downstream signaling by altering phosphorylation-driven interactions that promote growth and survival. Secretory Carrier Membrane Pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Venugopalan, Abhilash, Lynberg, Matthew, Cultraro, Constance M., Nguyen, Khoa Dang P., Zhang, Xu, Waris, Maryam, Dayal, Noelle, Abebe, Asebot, Maity, Tapan K., Guha, Udayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514158/
https://www.ncbi.nlm.nih.gov/pubmed/33850265
http://dx.doi.org/10.1038/s41388-021-01764-y

Ejemplares similares