A Human Dectin-2 Deficiency Associated With Invasive Aspergillosis

Immunocompromised patients are highly susceptible to invasive aspergillosis. Herein, we identified a homozygous deletion mutation (507 del C) resulting in a frameshift (N170I) and early stop codon in the fungal binding Dectin-2 receptor, in an immunocompromised patient. The mutated form of Dectin-2...

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Detalles Bibliográficos
Autores principales: Griffiths, James S, White, P Lewis, Czubala, Magdalena A, Simonazzi, Elena, Bruno, Mariolina, Thompson, Aiysha, Rizkallah, Pierre J, Gurney, Mark, da Fonseca, Diogo M, Naglik, Julian R, Ingram, Wendy, Wilson, Keith, van de Veerdonk, Frank L, Barnes, Rosemary, Taylor, Philip R, Orr, Selinda J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514184/
https://www.ncbi.nlm.nih.gov/pubmed/33733279
http://dx.doi.org/10.1093/infdis/jiab145

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