A Randomized Clinical Trial to Compare Plasmodium falciparum Gametocytemia and Infectivity After Blood-Stage or Mosquito Bite–Induced Controlled Malaria Infection

BACKGROUND: For malaria elimination efforts, it is important to better understand parasite transmission to mosquitoes and develop models for early-clinical evaluation of transmission-blocking interventions. METHODS: In a randomized open-label trial, 24 participants were infected by bites from Plasmo...

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Detalles Bibliográficos
Autores principales: Alkema, Manon, Reuling, Isaie J, de Jong, Gerdie M, Lanke, Kjerstin, Coffeng, Luc E, van Gemert, Geert-Jan, van de Vegte-Bolmer, Marga, de Mast, Quirijn, van Crevel, Reinout, Ivinson, Karen, Ockenhouse, Christian F, McCarthy, James S, Sauerwein, Robert, Collins, Katharine A, Bousema, Teun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514191/
https://www.ncbi.nlm.nih.gov/pubmed/32239171
http://dx.doi.org/10.1093/infdis/jiaa157

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