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In silico design of quadruplex aptamers against the spike protein of SARS-CoV-2

Nucleic acid aptamers are short sequences of nucleic acid ligands that bind to a specific target molecule. Aptamers are experimentally nominated using the well-designed SELEX (systematic evolution of ligands by exponential enrichment) method. Here, we designed a new method for diagnosis and blocking...

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Detalles Bibliográficos
Autores principales: Behbahani, Mandana, Mohabatkar, Hassan, Hosseini, Barumand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514331/
https://www.ncbi.nlm.nih.gov/pubmed/34664030
http://dx.doi.org/10.1016/j.imu.2021.100757

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