Patent foramen ovale closure in India; Feasibility, challenges and mid-term outcomes

Patent foramen ovale closure (PFO) is an underutilized therapy, and our study explored the challenges and feasibility of PFO closure in the Indian setting. Eighty patients with Embolic Stroke of Undetermined Source (ESUS) were screened by transcranial Doppler (TCD) for PFO. Twenty-nine patients unde...

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Detalles Bibliográficos
Autores principales: Thomson, Viji S., Aaron, Sanjith, Samson D, Nathaniel, Krupa, Jesu, Prabhakar, A.T., Jose, John, George, Paul, George, Oommen K., Joseph, George, Yadav, Bijesh Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Brief
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514405/
https://www.ncbi.nlm.nih.gov/pubmed/34627589
http://dx.doi.org/10.1016/j.ihj.2021.09.001
Descripción
Sumario:Patent foramen ovale closure (PFO) is an underutilized therapy, and our study explored the challenges and feasibility of PFO closure in the Indian setting. Eighty patients with Embolic Stroke of Undetermined Source (ESUS) were screened by transcranial Doppler (TCD) for PFO. Twenty-nine patients underwent successful closure. High-risk features of a long tunnel, inter-atrial septal aneurysm, and large defect were present in 31%, 28%, and 59%. Transcranial Doppler had a sensitivity and specificity of 78% and 53% (p = 0.02) to detect PFO. Anticoagulation was withdrawn in 85% of patients post closure. Two patients had residual shunts at follow-up of 19 (9,34) months.

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