Patent foramen ovale closure in India; Feasibility, challenges and mid-term outcomes

Patent foramen ovale closure (PFO) is an underutilized therapy, and our study explored the challenges and feasibility of PFO closure in the Indian setting. Eighty patients with Embolic Stroke of Undetermined Source (ESUS) were screened by transcranial Doppler (TCD) for PFO. Twenty-nine patients unde...

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Autores principales: Thomson, Viji S., Aaron, Sanjith, Samson D, Nathaniel, Krupa, Jesu, Prabhakar, A.T., Jose, John, George, Paul, George, Oommen K., Joseph, George, Yadav, Bijesh Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Brief
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514405/
https://www.ncbi.nlm.nih.gov/pubmed/34627589
http://dx.doi.org/10.1016/j.ihj.2021.09.001
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author Thomson, Viji S.
Aaron, Sanjith
Samson D, Nathaniel
Krupa, Jesu
Prabhakar, A.T.
Jose, John
George, Paul
George, Oommen K.
Joseph, George
Yadav, Bijesh Kumar
author_facet Thomson, Viji S.
Aaron, Sanjith
Samson D, Nathaniel
Krupa, Jesu
Prabhakar, A.T.
Jose, John
George, Paul
George, Oommen K.
Joseph, George
Yadav, Bijesh Kumar
author_sort Thomson, Viji S.
collection PubMed
description Patent foramen ovale closure (PFO) is an underutilized therapy, and our study explored the challenges and feasibility of PFO closure in the Indian setting. Eighty patients with Embolic Stroke of Undetermined Source (ESUS) were screened by transcranial Doppler (TCD) for PFO. Twenty-nine patients underwent successful closure. High-risk features of a long tunnel, inter-atrial septal aneurysm, and large defect were present in 31%, 28%, and 59%. Transcranial Doppler had a sensitivity and specificity of 78% and 53% (p = 0.02) to detect PFO. Anticoagulation was withdrawn in 85% of patients post closure. Two patients had residual shunts at follow-up of 19 (9,34) months.
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spelling pubmed-85144052021-10-21 Patent foramen ovale closure in India; Feasibility, challenges and mid-term outcomes Thomson, Viji S. Aaron, Sanjith Samson D, Nathaniel Krupa, Jesu Prabhakar, A.T. Jose, John George, Paul George, Oommen K. Joseph, George Yadav, Bijesh Kumar Indian Heart J Research Brief Patent foramen ovale closure (PFO) is an underutilized therapy, and our study explored the challenges and feasibility of PFO closure in the Indian setting. Eighty patients with Embolic Stroke of Undetermined Source (ESUS) were screened by transcranial Doppler (TCD) for PFO. Twenty-nine patients underwent successful closure. High-risk features of a long tunnel, inter-atrial septal aneurysm, and large defect were present in 31%, 28%, and 59%. Transcranial Doppler had a sensitivity and specificity of 78% and 53% (p = 0.02) to detect PFO. Anticoagulation was withdrawn in 85% of patients post closure. Two patients had residual shunts at follow-up of 19 (9,34) months. Elsevier 2021 2021-09-06 /pmc/articles/PMC8514405/ /pubmed/34627589 http://dx.doi.org/10.1016/j.ihj.2021.09.001 Text en © 2021 Cardiological Society of India. Published by Elsevier B.V. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Brief
Thomson, Viji S.
Aaron, Sanjith
Samson D, Nathaniel
Krupa, Jesu
Prabhakar, A.T.
Jose, John
George, Paul
George, Oommen K.
Joseph, George
Yadav, Bijesh Kumar
Patent foramen ovale closure in India; Feasibility, challenges and mid-term outcomes
title Patent foramen ovale closure in India; Feasibility, challenges and mid-term outcomes
title_full Patent foramen ovale closure in India; Feasibility, challenges and mid-term outcomes
title_fullStr Patent foramen ovale closure in India; Feasibility, challenges and mid-term outcomes
title_full_unstemmed Patent foramen ovale closure in India; Feasibility, challenges and mid-term outcomes
title_short Patent foramen ovale closure in India; Feasibility, challenges and mid-term outcomes
title_sort patent foramen ovale closure in india; feasibility, challenges and mid-term outcomes
topic Research Brief
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514405/
https://www.ncbi.nlm.nih.gov/pubmed/34627589
http://dx.doi.org/10.1016/j.ihj.2021.09.001
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