Oral administration of E-type prostanoid (EP) 1 receptor antagonist suppresses carcinogenesis and development of prostate cancer via upregulation of apoptosis in an animal model

Prostaglandin E2 plays an important role in carcinogenesis and malignant potential of prostate cancer (PC) cells by binding to its specific receptors, E-type prostanoid (EP) receptors. However, anti-carcinogenic effects of the EP receptor antagonist are unclear. In this study, we used a mouse model...

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Detalles Bibliográficos
Autores principales: Masato, Masahito, Miyata, Yasuyoshi, Kurata, Hiroki, Ito, Hidenori, Mitsunari, Kensuke, Asai, Akihiro, Nakamura, Yuichiro, Araki, Kyohei, Mukae, Yuta, Matsuda, Tsuyoshi, Harada, Junki, Matsuo, Tomohiro, Ohba, Kojiro, Sakai, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514456/
https://www.ncbi.nlm.nih.gov/pubmed/34645904
http://dx.doi.org/10.1038/s41598-021-99694-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514456/
https://www.ncbi.nlm.nih.gov/pubmed/34645904
http://dx.doi.org/10.1038/s41598-021-99694-y

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