Cargando…
The cyclin dependent kinase inhibitor Roscovitine prevents diet-induced metabolic disruption in obese mice
Most strategies to treat obesity-related disorders have involved prevention of diet-induced weight gain in lean mice. Treatment of obese individuals will require therapies that reverse the detrimental effects of excess body weight. Cyclin-dependent kinases have been shown to contribute to obesity an...
Autores principales: | Rabhi, Nabil, Desevin, Kathleen, Cortez, Briana Noel, Hekman, Ryan, Lin, Jean Z., Emili, Andrew, Farmer, Stephen R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514475/ https://www.ncbi.nlm.nih.gov/pubmed/34645915 http://dx.doi.org/10.1038/s41598-021-99871-z |
Ejemplares similares
-
Shifts of Immune Cell Populations Differ in Response to Different Effectors of Beige Remodeling of Adipose Tissue
por: Rabhi, Nabil, et al.
Publicado: (2020) -
Several Human Cyclin-Dependent Kinase Inhibitors, Structurally Related to Roscovitine, As New Anti-Malarial Agents
por: Houzé, Sandrine, et al.
Publicado: (2014) -
Human embryonic stem cells display a pronounced sensitivity to the cyclin dependent kinase inhibitor Roscovitine
por: Videla-Richardson, Guillermo A., et al.
Publicado: (2019) -
Obesity-induced senescent macrophages activate a fibrotic transcriptional program in adipocyte progenitors
por: Rabhi, Nabil, et al.
Publicado: (2022) -
Cyclin-dependent kinase inhibitor r-roscovitine reduces lipoteichoic acid lung inflammation and improves the resolution of antibiotic-treated Streptococcus pneumoniae pneumonia
por: Hoogendijk, AJ, et al.
Publicado: (2009)