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The cyclin dependent kinase inhibitor Roscovitine prevents diet-induced metabolic disruption in obese mice

Most strategies to treat obesity-related disorders have involved prevention of diet-induced weight gain in lean mice. Treatment of obese individuals will require therapies that reverse the detrimental effects of excess body weight. Cyclin-dependent kinases have been shown to contribute to obesity an...

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Detalles Bibliográficos
Autores principales: Rabhi, Nabil, Desevin, Kathleen, Cortez, Briana Noel, Hekman, Ryan, Lin, Jean Z., Emili, Andrew, Farmer, Stephen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514475/
https://www.ncbi.nlm.nih.gov/pubmed/34645915
http://dx.doi.org/10.1038/s41598-021-99871-z

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