Targeted clearance of senescent cells using an antibody-drug conjugate against a specific membrane marker

A wide range of diseases have been shown to be influenced by the accumulation of senescent cells, from fibrosis to diabetes, cancer, Alzheimer’s and other age-related pathologies. Consistent with this, clearance of senescent cells can prolong healthspan and lifespan in in vivo models. This provided...

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Detalles Bibliográficos
Autores principales: Poblocka, Marta, Bassey, Akang Leonard, Smith, Victoria M., Falcicchio, Marta, Manso, Ana Sousa, Althubiti, Mohammad, Sheng, XiaoBo, Kyle, Andrew, Barber, Ruth, Frigerio, Mark, Macip, Salvador
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514501/
https://www.ncbi.nlm.nih.gov/pubmed/34645909
http://dx.doi.org/10.1038/s41598-021-99852-2

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