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Structural basis of the P4B ATPase lipid flippase activity

P4 ATPases are lipid flippases that are phylogenetically grouped into P4A, P4B and P4C clades. The P4A ATPases are heterodimers composed of a catalytic α-subunit and accessory β-subunit, and the structures of several heterodimeric flippases have been reported. The S. cerevisiae Neo1 and its ortholog...

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Detalles Bibliográficos
Autores principales:	Bai, Lin, Jain, Bhawik K., You, Qinglong, Duan, H. Diessel, Takar, Mehmet, Graham, Todd R., Li, Huilin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514546/ https://www.ncbi.nlm.nih.gov/pubmed/34645814 http://dx.doi.org/10.1038/s41467-021-26273-0

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