Mechanical Strain Regulates Myofibroblast Differentiation of Human Scleral Fibroblasts by YAP

Scleral extracellular matrix (ECM) remodeling is thought to play a critical role in the pathogenesis of glaucoma. Mechanical strain induced by elevated intraocular pressure can promote myofibroblast differentiation of fibroblasts and result in scleral ECM remodeling; however, the underlying mechanis...

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Detalles Bibliográficos
Autores principales: Hu, Di, Jiang, Junhong, Ding, Baiyang, Xue, Kang, Sun, Xinghuai, Qian, Shaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514697/
https://www.ncbi.nlm.nih.gov/pubmed/34658907
http://dx.doi.org/10.3389/fphys.2021.712509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514697/
https://www.ncbi.nlm.nih.gov/pubmed/34658907
http://dx.doi.org/10.3389/fphys.2021.712509

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