NFIL3 Facilitates Neutrophil Autophagy, Neutrophil Extracellular Trap Formation and Inflammation During Gout via REDD1-Dependent mTOR Inactivation

Autophagy pathways play an important role in immunity and inflammation via pathogen clearance mechanisms mediated by immune cells, such as macrophages and neutrophils. In particular, autophagic activity is essential for the release of neutrophil extracellular traps (NETs), a distinct form of active...

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Detalles Bibliográficos
Autores principales: Tang, Honghu, Tan, Chunyu, Cao, Xue, Liu, Yi, Zhao, Hua, Zhao, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514722/
https://www.ncbi.nlm.nih.gov/pubmed/34660620
http://dx.doi.org/10.3389/fmed.2021.692781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514722/
https://www.ncbi.nlm.nih.gov/pubmed/34660620
http://dx.doi.org/10.3389/fmed.2021.692781

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