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Reversible conduction block of peroneal nerve associated with SARS-CoV-2

BACKGROUND: The ongoing SARS-CoV-2 pandemic, which is dramatically spreading worldwide, is well known for its respiratory sequelae. Besides cases of Guillain-Barré Syndrome, encephalitis, hyposmia, the whole range of neurological complications due to SARSCoV-2 is still not well known. METHODS AND FI...

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Autores principales: Cioffi, Ettore, Dilenola, Davide, Iuliano, Luigi, Polidoro, Alessandro, Casali, Carlo, Serrao, Mariano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514806/
https://www.ncbi.nlm.nih.gov/pubmed/34648103
http://dx.doi.org/10.1007/s10072-021-05655-8
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author Cioffi, Ettore
Dilenola, Davide
Iuliano, Luigi
Polidoro, Alessandro
Casali, Carlo
Serrao, Mariano
author_facet Cioffi, Ettore
Dilenola, Davide
Iuliano, Luigi
Polidoro, Alessandro
Casali, Carlo
Serrao, Mariano
author_sort Cioffi, Ettore
collection PubMed
description BACKGROUND: The ongoing SARS-CoV-2 pandemic, which is dramatically spreading worldwide, is well known for its respiratory sequelae. Besides cases of Guillain-Barré Syndrome, encephalitis, hyposmia, the whole range of neurological complications due to SARSCoV-2 is still not well known. METHODS AND FINDINGS: Herein, we report a new case of COVID-19, associated with mononeuropathy with reversible conduction block (CB). After SARS-CoV-2 infection, the patient developed acute weakness of left peroneal muscles. He underwent an endovenous immunoglobulin treatment, and symptoms improved. Two electroneurographic exam (before and after treatment), showed a reversible CB on left peroneal nerve. Dosage of serum antiganglioside antibodies showed anti-GM1 IgM positivity. CONCLUSIONS: The present case gives new informations about reversible CB neuropathy as an acute presentation of SARS-CoV-2. Besides, antiganglioside antibodies evaluation could be useful to understand etiology of the increasing number of neurological manifestations related to SARS-CoV-2.
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spelling pubmed-85148062021-10-14 Reversible conduction block of peroneal nerve associated with SARS-CoV-2 Cioffi, Ettore Dilenola, Davide Iuliano, Luigi Polidoro, Alessandro Casali, Carlo Serrao, Mariano Neurol Sci Covid-19 BACKGROUND: The ongoing SARS-CoV-2 pandemic, which is dramatically spreading worldwide, is well known for its respiratory sequelae. Besides cases of Guillain-Barré Syndrome, encephalitis, hyposmia, the whole range of neurological complications due to SARSCoV-2 is still not well known. METHODS AND FINDINGS: Herein, we report a new case of COVID-19, associated with mononeuropathy with reversible conduction block (CB). After SARS-CoV-2 infection, the patient developed acute weakness of left peroneal muscles. He underwent an endovenous immunoglobulin treatment, and symptoms improved. Two electroneurographic exam (before and after treatment), showed a reversible CB on left peroneal nerve. Dosage of serum antiganglioside antibodies showed anti-GM1 IgM positivity. CONCLUSIONS: The present case gives new informations about reversible CB neuropathy as an acute presentation of SARS-CoV-2. Besides, antiganglioside antibodies evaluation could be useful to understand etiology of the increasing number of neurological manifestations related to SARS-CoV-2. Springer International Publishing 2021-10-14 2022 /pmc/articles/PMC8514806/ /pubmed/34648103 http://dx.doi.org/10.1007/s10072-021-05655-8 Text en © Fondazione Società Italiana di Neurologia 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Covid-19
Cioffi, Ettore
Dilenola, Davide
Iuliano, Luigi
Polidoro, Alessandro
Casali, Carlo
Serrao, Mariano
Reversible conduction block of peroneal nerve associated with SARS-CoV-2
title Reversible conduction block of peroneal nerve associated with SARS-CoV-2
title_full Reversible conduction block of peroneal nerve associated with SARS-CoV-2
title_fullStr Reversible conduction block of peroneal nerve associated with SARS-CoV-2
title_full_unstemmed Reversible conduction block of peroneal nerve associated with SARS-CoV-2
title_short Reversible conduction block of peroneal nerve associated with SARS-CoV-2
title_sort reversible conduction block of peroneal nerve associated with sars-cov-2
topic Covid-19
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514806/
https://www.ncbi.nlm.nih.gov/pubmed/34648103
http://dx.doi.org/10.1007/s10072-021-05655-8
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