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Reversible conduction block of peroneal nerve associated with SARS-CoV-2
BACKGROUND: The ongoing SARS-CoV-2 pandemic, which is dramatically spreading worldwide, is well known for its respiratory sequelae. Besides cases of Guillain-Barré Syndrome, encephalitis, hyposmia, the whole range of neurological complications due to SARSCoV-2 is still not well known. METHODS AND FI...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514806/ https://www.ncbi.nlm.nih.gov/pubmed/34648103 http://dx.doi.org/10.1007/s10072-021-05655-8 |
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author | Cioffi, Ettore Dilenola, Davide Iuliano, Luigi Polidoro, Alessandro Casali, Carlo Serrao, Mariano |
author_facet | Cioffi, Ettore Dilenola, Davide Iuliano, Luigi Polidoro, Alessandro Casali, Carlo Serrao, Mariano |
author_sort | Cioffi, Ettore |
collection | PubMed |
description | BACKGROUND: The ongoing SARS-CoV-2 pandemic, which is dramatically spreading worldwide, is well known for its respiratory sequelae. Besides cases of Guillain-Barré Syndrome, encephalitis, hyposmia, the whole range of neurological complications due to SARSCoV-2 is still not well known. METHODS AND FINDINGS: Herein, we report a new case of COVID-19, associated with mononeuropathy with reversible conduction block (CB). After SARS-CoV-2 infection, the patient developed acute weakness of left peroneal muscles. He underwent an endovenous immunoglobulin treatment, and symptoms improved. Two electroneurographic exam (before and after treatment), showed a reversible CB on left peroneal nerve. Dosage of serum antiganglioside antibodies showed anti-GM1 IgM positivity. CONCLUSIONS: The present case gives new informations about reversible CB neuropathy as an acute presentation of SARS-CoV-2. Besides, antiganglioside antibodies evaluation could be useful to understand etiology of the increasing number of neurological manifestations related to SARS-CoV-2. |
format | Online Article Text |
id | pubmed-8514806 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-85148062021-10-14 Reversible conduction block of peroneal nerve associated with SARS-CoV-2 Cioffi, Ettore Dilenola, Davide Iuliano, Luigi Polidoro, Alessandro Casali, Carlo Serrao, Mariano Neurol Sci Covid-19 BACKGROUND: The ongoing SARS-CoV-2 pandemic, which is dramatically spreading worldwide, is well known for its respiratory sequelae. Besides cases of Guillain-Barré Syndrome, encephalitis, hyposmia, the whole range of neurological complications due to SARSCoV-2 is still not well known. METHODS AND FINDINGS: Herein, we report a new case of COVID-19, associated with mononeuropathy with reversible conduction block (CB). After SARS-CoV-2 infection, the patient developed acute weakness of left peroneal muscles. He underwent an endovenous immunoglobulin treatment, and symptoms improved. Two electroneurographic exam (before and after treatment), showed a reversible CB on left peroneal nerve. Dosage of serum antiganglioside antibodies showed anti-GM1 IgM positivity. CONCLUSIONS: The present case gives new informations about reversible CB neuropathy as an acute presentation of SARS-CoV-2. Besides, antiganglioside antibodies evaluation could be useful to understand etiology of the increasing number of neurological manifestations related to SARS-CoV-2. Springer International Publishing 2021-10-14 2022 /pmc/articles/PMC8514806/ /pubmed/34648103 http://dx.doi.org/10.1007/s10072-021-05655-8 Text en © Fondazione Società Italiana di Neurologia 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Covid-19 Cioffi, Ettore Dilenola, Davide Iuliano, Luigi Polidoro, Alessandro Casali, Carlo Serrao, Mariano Reversible conduction block of peroneal nerve associated with SARS-CoV-2 |
title | Reversible conduction block of peroneal nerve associated with SARS-CoV-2 |
title_full | Reversible conduction block of peroneal nerve associated with SARS-CoV-2 |
title_fullStr | Reversible conduction block of peroneal nerve associated with SARS-CoV-2 |
title_full_unstemmed | Reversible conduction block of peroneal nerve associated with SARS-CoV-2 |
title_short | Reversible conduction block of peroneal nerve associated with SARS-CoV-2 |
title_sort | reversible conduction block of peroneal nerve associated with sars-cov-2 |
topic | Covid-19 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514806/ https://www.ncbi.nlm.nih.gov/pubmed/34648103 http://dx.doi.org/10.1007/s10072-021-05655-8 |
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