Case Report: A Novel Activating FLT3 Mutation in Acute Myeloid Leukemia

FMS-like tyrosine kinase 3 (FLT3) is among the most common driver genes recurrently mutated in acute myeloid leukemia (AML), accounting for approximately 30% of cases. Activating mutations of the FLT3 receptor include internal tandem duplications (ITD) that map to the auto-inhibitory juxtamembrane (...

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Detalles Bibliográficos
Autores principales: Bruno, Samantha, Bandini, Lorenza, Patuelli, Agnese, Robustelli, Valentina, Venturi, Claudia, Mancini, Manuela, Forte, Dorian, De Santis, Sara, Monaldi, Cecilia, Grassi, Alessandra, Chiurumbolo, Gabriella, Paolini, Stefania, Cristiano, Gianluca, Papayannidis, Cristina, Sartor, Chiara, Nanni, Jacopo, Ottaviani, Emanuela, Curti, Antonio, Cavo, Michele, Soverini, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514815/
https://www.ncbi.nlm.nih.gov/pubmed/34660293
http://dx.doi.org/10.3389/fonc.2021.728613

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