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Primary Intraocular Lymphoma in a Patient with Bilateral Epstein-Barr Virus Panuveitis
PURPOSE: Herein, we report a case of primary intraocular lymphoma (PIOL) with the first presentation of bilateral Epstein-Barr virus- (EBV-) associated panuveitis. Case Presentation. A 69-year-old male was referred with a three-day history of blurred vision and pain and redness in his left eye follo...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514923/ https://www.ncbi.nlm.nih.gov/pubmed/34659852 http://dx.doi.org/10.1155/2021/9496173 |
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author | Hosseini, Seyedeh Maryam Abrishami, Mojtaba Barashki, Elham Zamani, Ghodsieh |
author_facet | Hosseini, Seyedeh Maryam Abrishami, Mojtaba Barashki, Elham Zamani, Ghodsieh |
author_sort | Hosseini, Seyedeh Maryam |
collection | PubMed |
description | PURPOSE: Herein, we report a case of primary intraocular lymphoma (PIOL) with the first presentation of bilateral Epstein-Barr virus- (EBV-) associated panuveitis. Case Presentation. A 69-year-old male was referred with a three-day history of blurred vision and pain and redness in his left eye following cataract surgery. Examination revealed panuveitis, vitritis, and necrotizing retinitis with retinal hemorrhage. A month later, the right eye was also involved. Polymerase chain reaction-based analysis of the vitreous sample was positive for EBV, and cytological evaluation was compatible with the diagnosis of B-cell lymphoma. A significant improvement was observed following serial intravitreal rituximab and methotrexate injections. The central nervous system and lungs were involved after 6 months, and the patient expired despite systemic chemotherapy. CONCLUSION: There may be an association between EBV panuveitis and primary intraocular B-cell lymphoma. |
format | Online Article Text |
id | pubmed-8514923 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-85149232021-10-15 Primary Intraocular Lymphoma in a Patient with Bilateral Epstein-Barr Virus Panuveitis Hosseini, Seyedeh Maryam Abrishami, Mojtaba Barashki, Elham Zamani, Ghodsieh Case Rep Ophthalmol Med Case Report PURPOSE: Herein, we report a case of primary intraocular lymphoma (PIOL) with the first presentation of bilateral Epstein-Barr virus- (EBV-) associated panuveitis. Case Presentation. A 69-year-old male was referred with a three-day history of blurred vision and pain and redness in his left eye following cataract surgery. Examination revealed panuveitis, vitritis, and necrotizing retinitis with retinal hemorrhage. A month later, the right eye was also involved. Polymerase chain reaction-based analysis of the vitreous sample was positive for EBV, and cytological evaluation was compatible with the diagnosis of B-cell lymphoma. A significant improvement was observed following serial intravitreal rituximab and methotrexate injections. The central nervous system and lungs were involved after 6 months, and the patient expired despite systemic chemotherapy. CONCLUSION: There may be an association between EBV panuveitis and primary intraocular B-cell lymphoma. Hindawi 2021-10-06 /pmc/articles/PMC8514923/ /pubmed/34659852 http://dx.doi.org/10.1155/2021/9496173 Text en Copyright © 2021 Seyedeh Maryam Hosseini et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Hosseini, Seyedeh Maryam Abrishami, Mojtaba Barashki, Elham Zamani, Ghodsieh Primary Intraocular Lymphoma in a Patient with Bilateral Epstein-Barr Virus Panuveitis |
title | Primary Intraocular Lymphoma in a Patient with Bilateral Epstein-Barr Virus Panuveitis |
title_full | Primary Intraocular Lymphoma in a Patient with Bilateral Epstein-Barr Virus Panuveitis |
title_fullStr | Primary Intraocular Lymphoma in a Patient with Bilateral Epstein-Barr Virus Panuveitis |
title_full_unstemmed | Primary Intraocular Lymphoma in a Patient with Bilateral Epstein-Barr Virus Panuveitis |
title_short | Primary Intraocular Lymphoma in a Patient with Bilateral Epstein-Barr Virus Panuveitis |
title_sort | primary intraocular lymphoma in a patient with bilateral epstein-barr virus panuveitis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514923/ https://www.ncbi.nlm.nih.gov/pubmed/34659852 http://dx.doi.org/10.1155/2021/9496173 |
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