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Large-scale analysis of imprinting in naive human pluripotent stem cells reveals recurrent aberrations and a potential link to FGF signaling

Genomic imprinting is a parent-of-origin dependent monoallelic expression of genes. Previous studies showed that conversion of primed human pluripotent stem cells (hPSCs) into naive pluripotency is accompanied by genome-wide loss of methylation that includes imprinted loci. However, the extent of ab...

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Detalles Bibliográficos
Autores principales:	Keshet, Gal, Benvenisty, Nissim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514966/ https://www.ncbi.nlm.nih.gov/pubmed/34597600 http://dx.doi.org/10.1016/j.stemcr.2021.09.002

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