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Hepatic Krüppel-like factor 16 (KLF16) targets PPARα to improve steatohepatitis and insulin resistance

OBJECTIVE: Impaired hepatic fatty acids oxidation results in lipid accumulation and redox imbalance, promoting the development of fatty liver diseases and insulin resistance. However, the underlying pathogenic mechanism is poorly understood. Krüppel-like factor 16 (KLF16) is a transcription factor t...

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Detalles Bibliográficos
Autores principales:	Sun, Nannan, Shen, Chuangpeng, Zhang, Lei, Wu, Xiaojie, Yu, Yuanyuan, Yang, Xiaoying, Yang, Chen, Zhong, Chong, Gao, Zhao, Miao, Wei, Yang, Zehong, Gao, Weihang, Hu, Ling, Williams, Kevin, Liu, Changhui, Chang, Yongsheng, Gao, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Hepatology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515101/ https://www.ncbi.nlm.nih.gov/pubmed/33257471 http://dx.doi.org/10.1136/gutjnl-2020-321774

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