A GD2-aptamer-mediated, self-assembling nanomedicine for targeted multiple treatments in neuroblastoma theranostics

Because current mainstream anti-glycolipid GD2 therapeutics for neuroblastoma (NB) have limitations, such as severe adverse effects, improved therapeutics are needed. In this study, we developed a GD2 aptamer (DB99) and constructed a GD2-aptamer-mediated multifunctional nanomedicine (ANM) with effec...

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Detalles Bibliográficos
Autores principales: Zhang, Liyu, Wang, Meng, Zhu, Zeen, Chen, Shengquan, Wu, Haibin, Yang, Ying, Che, Fengyu, Li, Qiao, Li, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515170/
https://www.ncbi.nlm.nih.gov/pubmed/34703655
http://dx.doi.org/10.1016/j.omtn.2021.08.021

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