Cargando…
Characterization of protein–ligand interactions by SABRE
Nuclear spin hyperpolarization through signal amplification by reversible exchange (SABRE), the non-hydrogenative version of para-hydrogen induced polarization, is demonstrated to enhance sensitivity for the detection of biomacromolecular interactions. A target ligand for the enzyme trypsin includes...
Autores principales: | Mandal, Ratnamala, Pham, Pierce, Hilty, Christian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515190/ https://www.ncbi.nlm.nih.gov/pubmed/34745525 http://dx.doi.org/10.1039/d1sc03404a |
Ejemplares similares
-
Biomolecular interactions studied by low-field NMR using SABRE hyperpolarization
por: Pham, Pierce, et al.
Publicado: (2023) -
Interfacing Liquid State Hyperpolarization Methods with NMR Instrumentation
por: Pham, Pierce, et al.
Publicado: (2022) -
Harnessing asymmetric N-heterocyclic carbene ligands to optimise SABRE hyperpolarisation
por: Wong, Chin Min, et al.
Publicado: (2018) -
Quantification of hyperpolarisation efficiency in SABRE and SABRE-Relay enhanced NMR spectroscopy
por: Richardson, Peter M., et al.
Publicado: (2018) -
Determination of protein–ligand binding modes using fast multi-dimensional NMR with hyperpolarization
por: Wang, Yunyi, et al.
Publicado: (2020)