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Evaluation of Risk Factors Affecting Outcome in Outborn Surgical Neonates

BACKGROUND: Mortality in surgical neonates contributes to neonatal mortality rates. The study was conceptualized to study clinical and nonclinical factors affecting mortality in surgical neonates so that timely intervention could result in improved survival of the neonates. MATERIALS AND METHODS: Th...

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Autores principales: Mohta, Anup, Mishra, Ashwani, Khan, Niyaz A., Jajoo, Mamta, Neogi, Sujoy, Sengar, Mamta, Gupta, Chhabi Ranu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515518/
https://www.ncbi.nlm.nih.gov/pubmed/34728915
http://dx.doi.org/10.4103/jiaps.JIAPS_149_20
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author Mohta, Anup
Mishra, Ashwani
Khan, Niyaz A.
Jajoo, Mamta
Neogi, Sujoy
Sengar, Mamta
Gupta, Chhabi Ranu
author_facet Mohta, Anup
Mishra, Ashwani
Khan, Niyaz A.
Jajoo, Mamta
Neogi, Sujoy
Sengar, Mamta
Gupta, Chhabi Ranu
author_sort Mohta, Anup
collection PubMed
description BACKGROUND: Mortality in surgical neonates contributes to neonatal mortality rates. The study was conceptualized to study clinical and nonclinical factors affecting mortality in surgical neonates so that timely intervention could result in improved survival of the neonates. MATERIALS AND METHODS: The study was initiated after approval from the institutional ethics committee and included 120 surgical neonates over a period of 18 months after obtaining consent from the parents/caregivers. Predesigned pro forma was used to record the details of antenatal care received, place of birth, travel history, maternal education and gestational age, and clinical condition at the time of admission. Values of biochemical tests such as serum electrolytes, serum creatinine, and arterial blood gasses were recorded. The need of inotrope support, blood or blood product transfusion, and postoperative ventilator support and intensive care unit (ICU) care was recorded. The results of the two groups, i.e., survivals and mortality, were compared. Outcome was recorded as mortality at 30 days or earlier. RESULTS: Irrespective of the surgical condition, the survival rate was significantly better in those babies who weighed more than 2.5 kg at the time of admission, had capillary refill time of <3 s, had serum ionized calcium levels more than 1 mmol/L, and did not require inotropes, blood or blood product transfusion, and postoperative ICU care and ventilator support. The place of birth, educational status of the mother, gestational age, and distance traveled for care had no statistically significant effect on survival. CONCLUSION: There is a statistically significant correlation between the survival of the babies who weighed more than 2.5 kg and are more physiologically preserved at the time of admission. Mortality rates can be decreased by timely interventions to reduce the need of inotropes, blood or blood products, and ICU care and ventilator support during their postoperative recovery.
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spelling pubmed-85155182021-11-01 Evaluation of Risk Factors Affecting Outcome in Outborn Surgical Neonates Mohta, Anup Mishra, Ashwani Khan, Niyaz A. Jajoo, Mamta Neogi, Sujoy Sengar, Mamta Gupta, Chhabi Ranu J Indian Assoc Pediatr Surg Original Article BACKGROUND: Mortality in surgical neonates contributes to neonatal mortality rates. The study was conceptualized to study clinical and nonclinical factors affecting mortality in surgical neonates so that timely intervention could result in improved survival of the neonates. MATERIALS AND METHODS: The study was initiated after approval from the institutional ethics committee and included 120 surgical neonates over a period of 18 months after obtaining consent from the parents/caregivers. Predesigned pro forma was used to record the details of antenatal care received, place of birth, travel history, maternal education and gestational age, and clinical condition at the time of admission. Values of biochemical tests such as serum electrolytes, serum creatinine, and arterial blood gasses were recorded. The need of inotrope support, blood or blood product transfusion, and postoperative ventilator support and intensive care unit (ICU) care was recorded. The results of the two groups, i.e., survivals and mortality, were compared. Outcome was recorded as mortality at 30 days or earlier. RESULTS: Irrespective of the surgical condition, the survival rate was significantly better in those babies who weighed more than 2.5 kg at the time of admission, had capillary refill time of <3 s, had serum ionized calcium levels more than 1 mmol/L, and did not require inotropes, blood or blood product transfusion, and postoperative ICU care and ventilator support. The place of birth, educational status of the mother, gestational age, and distance traveled for care had no statistically significant effect on survival. CONCLUSION: There is a statistically significant correlation between the survival of the babies who weighed more than 2.5 kg and are more physiologically preserved at the time of admission. Mortality rates can be decreased by timely interventions to reduce the need of inotropes, blood or blood products, and ICU care and ventilator support during their postoperative recovery. Wolters Kluwer - Medknow 2021 2021-09-16 /pmc/articles/PMC8515518/ /pubmed/34728915 http://dx.doi.org/10.4103/jiaps.JIAPS_149_20 Text en Copyright: © 2021 Journal of Indian Association of Pediatric Surgeons https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Mohta, Anup
Mishra, Ashwani
Khan, Niyaz A.
Jajoo, Mamta
Neogi, Sujoy
Sengar, Mamta
Gupta, Chhabi Ranu
Evaluation of Risk Factors Affecting Outcome in Outborn Surgical Neonates
title Evaluation of Risk Factors Affecting Outcome in Outborn Surgical Neonates
title_full Evaluation of Risk Factors Affecting Outcome in Outborn Surgical Neonates
title_fullStr Evaluation of Risk Factors Affecting Outcome in Outborn Surgical Neonates
title_full_unstemmed Evaluation of Risk Factors Affecting Outcome in Outborn Surgical Neonates
title_short Evaluation of Risk Factors Affecting Outcome in Outborn Surgical Neonates
title_sort evaluation of risk factors affecting outcome in outborn surgical neonates
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515518/
https://www.ncbi.nlm.nih.gov/pubmed/34728915
http://dx.doi.org/10.4103/jiaps.JIAPS_149_20
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