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Cosolutes Modify Alkaline Phosphatase Catalysis through Osmotic Stress and Crowding Mechanisms

[Image: see text] Examining the effects of different cosolutes on in vitro enzyme kinetics yielded glimpses into their potential behavior when functioning in their natural, complex, in vivo milieu. Viewing cosolute in vitro influences on a model enzyme, calf intestinal alkaline phosphatase, as a com...

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Detalles Bibliográficos
Autores principales: Yavorska, Oksana A., Syriste, Lukas, du Plessis, Chantal M., Yaqoob, Maryam, Loogman, Kyle, Cordara, Michael, Chik, John K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515568/
https://www.ncbi.nlm.nih.gov/pubmed/34660983
http://dx.doi.org/10.1021/acsomega.1c03243