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Diethylaminosulfur Trifluoride: A Novel, Low-Cost, Stable Double Thiolation Reagent for Imidazo[1,2-α]pyridines
[Image: see text] We report a novel, inexpensive double thiolation reagent that sulfurizes a broad range of imidazo[1,2-α]pyridines under mild conditions. Importantly, diethylaminosulfur trifluoride, as a common nucleophilic fluorinating reagent, was utilized as a novel thiolation reagent.
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515576/ https://www.ncbi.nlm.nih.gov/pubmed/34660986 http://dx.doi.org/10.1021/acsomega.1c03291 |
| _version_ | 1784583638611918848 |
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| author | Jiang, Hongmei Shen, Haicheng Zhu, Sha Wang, Binbin Yang, Yujie Nong, Zhibin Yi, Min Tang, Shiyun Gui, Qing-Wen |
| author_facet | Jiang, Hongmei Shen, Haicheng Zhu, Sha Wang, Binbin Yang, Yujie Nong, Zhibin Yi, Min Tang, Shiyun Gui, Qing-Wen |
| author_sort | Jiang, Hongmei |
| collection | PubMed |
| description | [Image: see text] We report a novel, inexpensive double thiolation reagent that sulfurizes a broad range of imidazo[1,2-α]pyridines under mild conditions. Importantly, diethylaminosulfur trifluoride, as a common nucleophilic fluorinating reagent, was utilized as a novel thiolation reagent. |
| format | Online Article Text |
| id | pubmed-8515576 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | American Chemical Society |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-85155762021-10-15 Diethylaminosulfur Trifluoride: A Novel, Low-Cost, Stable Double Thiolation Reagent for Imidazo[1,2-α]pyridines Jiang, Hongmei Shen, Haicheng Zhu, Sha Wang, Binbin Yang, Yujie Nong, Zhibin Yi, Min Tang, Shiyun Gui, Qing-Wen ACS Omega [Image: see text] We report a novel, inexpensive double thiolation reagent that sulfurizes a broad range of imidazo[1,2-α]pyridines under mild conditions. Importantly, diethylaminosulfur trifluoride, as a common nucleophilic fluorinating reagent, was utilized as a novel thiolation reagent. American Chemical Society 2021-09-28 /pmc/articles/PMC8515576/ /pubmed/34660986 http://dx.doi.org/10.1021/acsomega.1c03291 Text en © 2021 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by-nc-nd/4.0/Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
| spellingShingle | Jiang, Hongmei Shen, Haicheng Zhu, Sha Wang, Binbin Yang, Yujie Nong, Zhibin Yi, Min Tang, Shiyun Gui, Qing-Wen Diethylaminosulfur Trifluoride: A Novel, Low-Cost, Stable Double Thiolation Reagent for Imidazo[1,2-α]pyridines |
| title | Diethylaminosulfur Trifluoride: A Novel, Low-Cost,
Stable Double Thiolation Reagent for Imidazo[1,2-α]pyridines |
| title_full | Diethylaminosulfur Trifluoride: A Novel, Low-Cost,
Stable Double Thiolation Reagent for Imidazo[1,2-α]pyridines |
| title_fullStr | Diethylaminosulfur Trifluoride: A Novel, Low-Cost,
Stable Double Thiolation Reagent for Imidazo[1,2-α]pyridines |
| title_full_unstemmed | Diethylaminosulfur Trifluoride: A Novel, Low-Cost,
Stable Double Thiolation Reagent for Imidazo[1,2-α]pyridines |
| title_short | Diethylaminosulfur Trifluoride: A Novel, Low-Cost,
Stable Double Thiolation Reagent for Imidazo[1,2-α]pyridines |
| title_sort | diethylaminosulfur trifluoride: a novel, low-cost,
stable double thiolation reagent for imidazo[1,2-α]pyridines |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515576/ https://www.ncbi.nlm.nih.gov/pubmed/34660986 http://dx.doi.org/10.1021/acsomega.1c03291 |
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