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Hepatitis B virus persistent infection-related single nucleotide polymorphisms in HLA regions are associated with viral load in hepatoma families

BACKGROUND: Genome-wide association studies from Asia indicate that HLA-DP and HLA-DQ loci are important in persistent hepatitis B virus (HBV) infections. One of the key elements for HBV-related carcinogenesis is persistent viral replication and inflammation. AIM: To examine genetic and nongenetic f...

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Detalles Bibliográficos
Autores principales: Hsieh, Ai-Ru, Fann, Cathy S J, Lin, Hung-Chun, Tai, Jennifer, Hsieh, Sen-Yung, Tai, Dar-In
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515798/
https://www.ncbi.nlm.nih.gov/pubmed/34712031
http://dx.doi.org/10.3748/wjg.v27.i37.6262