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Characterizing batch effects and binding site-specific variability in ChIP-seq data

Multiple sources of variability can bias ChIP-seq data toward inferring transcription factor (TF) binding profiles. As ChIP-seq datasets increase in public repositories, it is now possible and necessary to account for complex sources of variability in ChIP-seq data analysis. We find that two types o...

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Detalles Bibliográficos
Autores principales: Teng, Mingxiang, Du, Dongliang, Chen, Danfeng, Irizarry, Rafael A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515842/
https://www.ncbi.nlm.nih.gov/pubmed/34661103
http://dx.doi.org/10.1093/nargab/lqab098