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Characterizing batch effects and binding site-specific variability in ChIP-seq data
Multiple sources of variability can bias ChIP-seq data toward inferring transcription factor (TF) binding profiles. As ChIP-seq datasets increase in public repositories, it is now possible and necessary to account for complex sources of variability in ChIP-seq data analysis. We find that two types o...
Autores principales: | Teng, Mingxiang, Du, Dongliang, Chen, Danfeng, Irizarry, Rafael A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515842/ https://www.ncbi.nlm.nih.gov/pubmed/34661103 http://dx.doi.org/10.1093/nargab/lqab098 |
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