A genetic element in the SARS-CoV-2 genome is shared with multiple insect species

SARS-CoV-2 is a member of the subgenus Sarbecovirus and thus contains the genetic element s2m. We have extensively mined nucleotide data in GenBank in order to obtain a comprehensive list of s2m sequences both in the four virus families where s2m has previously been described and in other groups of...

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Autores principales: Tengs, Torstein, Delwiche, Charles F., Monceyron Jonassen, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515862/
https://www.ncbi.nlm.nih.gov/pubmed/33427605
http://dx.doi.org/10.1099/jgv.0.001551
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author Tengs, Torstein
Delwiche, Charles F.
Monceyron Jonassen, Christine
author_facet Tengs, Torstein
Delwiche, Charles F.
Monceyron Jonassen, Christine
author_sort Tengs, Torstein
collection PubMed
description SARS-CoV-2 is a member of the subgenus Sarbecovirus and thus contains the genetic element s2m. We have extensively mined nucleotide data in GenBank in order to obtain a comprehensive list of s2m sequences both in the four virus families where s2m has previously been described and in other groups of organisms. Surprisingly, there seems to be a xenologue of s2m in a large number of insect species. The function of s2m is unknown, but our data show a very high degree of sequence conservation both in insects and in viruses and that the version of s2m found in SARS-CoV-2 has unique features, not seen in any other virus or insect strains.
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spelling pubmed-85158622021-10-15 A genetic element in the SARS-CoV-2 genome is shared with multiple insect species Tengs, Torstein Delwiche, Charles F. Monceyron Jonassen, Christine J Gen Virol Short Communication SARS-CoV-2 is a member of the subgenus Sarbecovirus and thus contains the genetic element s2m. We have extensively mined nucleotide data in GenBank in order to obtain a comprehensive list of s2m sequences both in the four virus families where s2m has previously been described and in other groups of organisms. Surprisingly, there seems to be a xenologue of s2m in a large number of insect species. The function of s2m is unknown, but our data show a very high degree of sequence conservation both in insects and in viruses and that the version of s2m found in SARS-CoV-2 has unique features, not seen in any other virus or insect strains. Microbiology Society 2021-01-11 /pmc/articles/PMC8515862/ /pubmed/33427605 http://dx.doi.org/10.1099/jgv.0.001551 Text en © 2021 The Authors https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License. The Microbiology Society waived the open access fees for this article.
spellingShingle Short Communication
Tengs, Torstein
Delwiche, Charles F.
Monceyron Jonassen, Christine
A genetic element in the SARS-CoV-2 genome is shared with multiple insect species
title A genetic element in the SARS-CoV-2 genome is shared with multiple insect species
title_full A genetic element in the SARS-CoV-2 genome is shared with multiple insect species
title_fullStr A genetic element in the SARS-CoV-2 genome is shared with multiple insect species
title_full_unstemmed A genetic element in the SARS-CoV-2 genome is shared with multiple insect species
title_short A genetic element in the SARS-CoV-2 genome is shared with multiple insect species
title_sort genetic element in the sars-cov-2 genome is shared with multiple insect species
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515862/
https://www.ncbi.nlm.nih.gov/pubmed/33427605
http://dx.doi.org/10.1099/jgv.0.001551
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