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Targeting novel structural and functional features of coronavirus protease nsp5 (3CL(pro), M(pro)) in the age of COVID-19

Coronavirus protease nsp5 (M((pro)), 3CL((pro))) remains a primary target for coronavirus therapeutics due to its indispensable and conserved role in the proteolytic processing of the viral replicase polyproteins. In this review, we discuss the diversity of known coronaviruses, the role of nsp5 in c...

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Detalles Bibliográficos
Autores principales:	Roe, Molly K., Junod, Nathan A., Young, Audrey R., Beachboard, Dia C., Stobart, Christopher C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Microbiology Society 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515871/ https://www.ncbi.nlm.nih.gov/pubmed/33507143 http://dx.doi.org/10.1099/jgv.0.001558

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