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Microdissection of the Bulk Transcriptome at Single-Cell Resolution Reveals Clinical Significance and Myeloid Cells Heterogeneity in Lung Adenocarcinoma

BACKGROUND: Tumor infiltrating myeloid (TIM) cells constitute a vital element of the tumor microenvironment. The cell-type heterogeneity of TIM has yet to be fully investigated. METHODS: We used a time saving approach to generate a single-cell reference matrix, allowing quantification of cell-type p...

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Detalles Bibliográficos
Autores principales:	Wu, Hao, Qin, Jiale, Zhao, Qiang, Lu, Lu, Li, Chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515901/ https://www.ncbi.nlm.nih.gov/pubmed/34659209 http://dx.doi.org/10.3389/fimmu.2021.723908

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