Comprehensive mapping of binding hot spots of SARS-CoV-2 RBD-specific neutralizing antibodies for tracking immune escape variants

BACKGROUND: The receptor-binding domain (RBD) variants of SARS-CoV-2 could impair antibody-mediated neutralization of the virus by host immunity; thus, prospective surveillance of antibody escape mutants and understanding the evolution of RBD are urgently needed. METHODS: Using the single B cell clo...

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Detalles Bibliográficos
Autores principales: Yi, Chunyan, Sun, Xiaoyu, Lin, Yixiao, Gu, Chenjian, Ding, Longfei, Lu, Xiao, Yang, Zhuo, Zhang, Yaguang, Ma, Liyan, Gu, Wangpeng, Qu, Aidong, Zhou, Xu, Li, Xiuling, Xu, Jianqing, Ling, Zhiyang, Xie, Youhua, Lu, Hongzhou, Sun, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8515915/
https://www.ncbi.nlm.nih.gov/pubmed/34649620
http://dx.doi.org/10.1186/s13073-021-00985-w

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