Fucosyltransferase 2 inhibitors: Identification via docking and STD-NMR studies

Fucosyltransferase 2 (FUT2) catalyzes the biosynthesis of A, B, and H antigens and other important glycans, such as (Sialyl Lewis(x)) sLe(x), and (Sialyl Lewis(y)) sLe(y). The production of these glycans is increased in various cancers, hence to design and develop specific inhibitors of FUT2 is a th...

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Detalles Bibliográficos
Autores principales: Zafar, Humaira, Atif, Muhammad, Atia-tul-Wahab, Choudhary, M. Iqbal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516197/
https://www.ncbi.nlm.nih.gov/pubmed/34648519
http://dx.doi.org/10.1371/journal.pone.0257623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516197/
https://www.ncbi.nlm.nih.gov/pubmed/34648519
http://dx.doi.org/10.1371/journal.pone.0257623

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