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Downregulation of mitochondrial biogenesis by virus infection triggers antiviral responses by cyclic GMP-AMP synthase

In general, in mammalian cells, cytosolic DNA viruses are sensed by cyclic GMP-AMP synthase (cGAS), and RNA viruses are recognized by retinoic acid-inducible gene I (RIG-I)-like receptors, triggering a series of downstream innate antiviral signaling steps in the host. We previously reported that mea...

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Detalles Bibliográficos
Autores principales: Sato, Hiroki, Hoshi, Miho, Ikeda, Fusako, Fujiyuki, Tomoko, Yoneda, Misako, Kai, Chieko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516216/
https://www.ncbi.nlm.nih.gov/pubmed/34648591
http://dx.doi.org/10.1371/journal.ppat.1009841

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