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Global Rhes knockout in the Q175 Huntington’s disease mouse model

Huntington’s disease (HD) results from an expansion mutation in the polyglutamine tract in huntingtin. Although huntingtin is ubiquitously expressed in the body, the striatum suffers the most severe pathology. Rhes is a Ras-related small GTP-binding protein highly expressed in the striatum that has...

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Detalles Bibliográficos
Autores principales:	Heikkinen, Taneli, Bragge, Timo, Kuosmanen, Juha, Parkkari, Teija, Gustafsson, Sanna, Kwan, Mei, Beltran, Jose, Ghavami, Afshin, Subramaniam, Srinivasa, Shahani, Neelam, Ramírez-Jarquín, Uri Nimrod, Park, Larry, Muñoz-Sanjuán, Ignacio, Marchionini, Deanna M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516231/ https://www.ncbi.nlm.nih.gov/pubmed/34648564 http://dx.doi.org/10.1371/journal.pone.0258486

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