Plasma ST6GAL1 regulates IgG sialylation to control IgA nephropathy progression

BACKGROUND: Our previous study revealed that plasma levels of a-2,6-sialyltransferase 1 (ST6GAL1) were increased in patients with IgA nephropathy (IgAN). ST6GAL1 catalyzes terminal sialylation of IgG to shift the antibody effector function to the anti-inflammatory pattern. However, the role of plasm...

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Detalles Bibliográficos
Autores principales: Liu, Youxia, Yu, Huyan, Wu, Sijing, Yang, Xia, Cao, Congcong, Wang, Fanghao, Jia, Junya, Yan, Tiekun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516375/
https://www.ncbi.nlm.nih.gov/pubmed/34729155
http://dx.doi.org/10.1177/20406223211048644

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516375/
https://www.ncbi.nlm.nih.gov/pubmed/34729155
http://dx.doi.org/10.1177/20406223211048644

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