Lead-Induced Motor Dysfunction Is Associated with Oxidative Stress, Proteome Modulation, and Neurodegeneration in Motor Cortex of Rats

Lead (Pb) is a toxic metal with great neurotoxic potential. The aim of this study was to investigate the effects of a long-term Pb intoxication on the global proteomic profile, oxidative biochemistry and neuronal density in motor cortex of adult rats, and the possible outcomes related to motor funct...

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Detalles Bibliográficos
Autores principales: Leão, Luana Ketlen Reis, Bittencourt, Leonardo Oliveira, Oliveira, Ana Carolina Alves, Nascimento, Priscila Cunha, Ferreira, Maria Karolina Martins, Miranda, Giza Hellen Nonato, Ferreira, Railson de Oliveira, Eiró-Quirino, Luciana, Puty, Bruna, Dionizio, Aline, Cartágenes, Sabrina Carvalho, Freire, Marco Aurelio M., Buzalaf, Marília Afonso Rabelo, Crespo-Lopez, Maria Elena, Maia, Cristiane Socorro Ferraz, Lima, Rafael Rodrigues
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516562/
https://www.ncbi.nlm.nih.gov/pubmed/34659634
http://dx.doi.org/10.1155/2021/5595047

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