Cargando…

TFE3 Regulates the Function of the Autophagy-Lysosome Pathway to Drive the Invasion and Metastasis of Papillary Thyroid Carcinoma

BACKGROUND: Accumulating evidence shows that autophagy plays a vital role in tumor occurrence, development, and metastasis and even determines tumor prognosis. However, little is known about its role in papillary thyroid carcinoma (PTC) or the potentially oncogenic role of TFE3 in regulating the aut...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Hongsheng, Zhu, Chumeng, Ruan, Yanyun, Fan, Lilong, Wei, Kena, Yang, Zhaohui, Chen, Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516586/ https://www.ncbi.nlm.nih.gov/pubmed/34660181 http://dx.doi.org/10.1155/2021/3081491

Ejemplares similares

hsa-miR-206b Involves in the Development of Papillary Thyroid Carcinoma via Targeting LMX1B
por: Lu, Hongsheng, et al.
Publicado: (2022)

T cell exhaustion is associated with the risk of papillary thyroid carcinoma and can be a predictive and sensitive biomarker for diagnosis
por: Zhu, Chumeng, et al.
Publicado: (2021)

TROP2 modulates the progression in papillary thyroid carcinoma
por: Sun, Huali, et al.
Publicado: (2021)

MYC competes with MiT/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostat
por: Annunziata, Ida, et al.
Publicado: (2019)

Markers of immune activation: novel biomarkers to predict the early-warning indicator of patients with papillary thyroid carcinoma
por: Lu, Hongsheng, et al.
Publicado: (2020)

CDK4/6 regulate lysosome biogenesis through TFEB/TFE3
por: Yin, Qiuyuan, et al.
Publicado: (2020)

TFEB and TFE3 drive kidney cystogenesis and tumorigenesis
por: Di Malta, Chiara, et al.
Publicado: (2023)

Analysis of Plasma EBV-DNA and Soluble Checkpoint Proteins in Nasopharyngeal Carcinoma Patients after Definitive Intensity-Modulated Radiotherapy
por: Ruan, Yanyun, et al.
Publicado: (2019)

NUPR1 promotes the proliferation and metastasis of oral squamous cell carcinoma cells by activating TFE3-dependent autophagy
por: Fan, Tengfei, et al.
Publicado: (2022)

The KEAP1–NRF2 pathway regulates TFEB/TFE3-dependent lysosomal biogenesis
por: Ong, Athena Jessica S., et al.
Publicado: (2023)

LDHA induces EMT gene transcription and regulates autophagy to promote the metastasis and tumorigenesis of papillary thyroid carcinoma
por: Hou, Xiukun, et al.
Publicado: (2021)

Genistein inhibits human papillary thyroid cancer cell detachment, invasion and metastasis
por: Zhang, Chunyan, et al.
Publicado: (2019)

Translation Inhibitors Activate Autophagy Master Regulators TFEB and TFE3
por: Dang, Thao Thi, et al.
Publicado: (2021)

TFE3-Mediated Autophagy is Involved in Dopaminergic Neurodegeneration in Parkinson’s Disease
por: He, Xin, et al.
Publicado: (2021)

Correction to: NUPR1 promotes the proliferation and metastasis of oral squamous cell carcinoma cells by activating TFE3-dependent autophagy
por: Fan, Tengfei, et al.
Publicado: (2022)

Fibronectin 1 promotes migration and invasion of papillary thyroid cancer and predicts papillary thyroid cancer lymph node metastasis
por: Xia, Shujun, et al.
Publicado: (2017)

Fibronectin 1 promotes migration and invasion of papillary thyroid cancer and predicts papillary thyroid cancer lymph node metastasis [Corrigendum]
Publicado: (2017)

LRRK2 suppresses lysosome degradative activity in macrophages and microglia through MiT-TFE transcription factor inhibition
por: Yadavalli, Narayana, et al.
Publicado: (2023)

A stress response p38 MAP kinase inhibitor SB202190 promoted TFEB/TFE3-dependent autophagy and lysosomal biogenesis independent of p38
por: Yang, Chuanbin, et al.
Publicado: (2020)

Lymph node metastasis of papillary thyroid carcinoma in the context of Hashimoto’s thyroiditis
por: Wang, Lirong, et al.
Publicado: (2022)

HEPES activates a MiT/TFE-dependent lysosomal-autophagic gene network in cultured cells: A call for caution
por: Tol, Marc J., et al.
Publicado: (2018)

Targeting TFE3 Protects Against Lysosomal Malfunction-Induced Pyroptosis in Random Skin Flaps via ROS Elimination
por: Li, Jiafeng, et al.
Publicado: (2021)

Inositol triphosphate–triggered calcium release from the endoplasmic reticulum induces lysosome biogenesis via TFEB/TFE3
por: Malek, Mouhannad, et al.
Publicado: (2022)

Multiparameter phenotypic screening for endogenous TFEB and TFE3 translocation identifies novel chemical series modulating lysosome function
por: Carling, Phillippa J, et al.
Publicado: (2022)

Papillary thyroid carcinoma with thyroiditis: lymph node metastasis, complications
por: Kim, Yon Seon, et al.
Publicado: (2013)

Brain metastasis from papillary thyroid carcinomas
por: TSUDA, KYOJI, et al.
Publicado: (2013)

Solitary Skin Metastasis of Papillary Thyroid Carcinoma
por: Kwon, Hyemi, et al.
Publicado: (2014)

Ectopic Papillary Thyroid Cancer with Distant Metastasis
por: Vázquez, Oscar R., et al.
Publicado: (2018)

Parapharyngeal metastasis from papillary thyroid microcarcinoma
por: Harrathi, Khaled, et al.
Publicado: (2020)

Cutaneous Metastasis from Papillary Carcinoma of Thyroid
por: Tomar, Suyash S., et al.
Publicado: (2019)

Papillary Thyroid Cancer Presenting as Skull Metastasis
por: Majety, Priyanka, et al.
Publicado: (2022)

miRNA dysregulation and the risk of metastasis and invasion in papillary thyroid cancer: a systematic review and meta-analysis
por: Wang, Tiantian, et al.
Publicado: (2017)

3,4‐Dimethoxychalcone induces autophagy through activation of the transcription factors TFE3 and TFEB
por: Chen, Guo, et al.
Publicado: (2019)

ESCRT-I fuels lysosomal degradation to restrict TFEB/TFE3 signaling via the Rag-mTORC1 pathway
por: Wróbel, Marta, et al.
Publicado: (2022)

Thyroid Metastasis from Breast Carcinoma Accompanied by Papillary Thyroid Carcinoma
por: Yang, Song-I, et al.
Publicado: (2014)

Sunitinib treatment promotes metastasis of drug-resistant renal cell carcinoma via TFE3 signaling pathway
por: Li, Luchao, et al.
Publicado: (2021)

Brain metastasis from papillary carcinoma of thyroid gland
por: Diyora, Batuk, et al.
Publicado: (2010)

Papillary carcinoma thyroid with metastasis to ectopic cervical thymus
por: Mushtaque, Majid, et al.
Publicado: (2011)

Predictive Factors of Skip Metastasis in Papillary Thyroid Cancer
por: Jin, Wen-Xu, et al.
Publicado: (2018)

Macrofollicular variant of papillary thyroid carcinoma with metastasis to femur
por: Candanedo-Gonzalez, Fernando, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_5qvfj6m8ou0as7oamtdl4b05f4