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Cannabis labelling is associated with genetic variation in terpene synthase genes

Analysis of over 100 Cannabis samples quantified for terpene and cannabinoid content and genotyped for over 100,000 single nucleotide polymorphisms indicated that Sativa- and Indica-labelled samples were genetically indistinct on a genome-wide scale. Instead, we found that Cannabis labelling was ass...

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Autores principales: Watts, Sophie, McElroy, Michel, Migicovsky, Zoë, Maassen, Hugo, van Velzen, Robin, Myles, Sean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516649/
https://www.ncbi.nlm.nih.gov/pubmed/34650264
http://dx.doi.org/10.1038/s41477-021-01003-y
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author Watts, Sophie
McElroy, Michel
Migicovsky, Zoë
Maassen, Hugo
van Velzen, Robin
Myles, Sean
author_facet Watts, Sophie
McElroy, Michel
Migicovsky, Zoë
Maassen, Hugo
van Velzen, Robin
Myles, Sean
author_sort Watts, Sophie
collection PubMed
description Analysis of over 100 Cannabis samples quantified for terpene and cannabinoid content and genotyped for over 100,000 single nucleotide polymorphisms indicated that Sativa- and Indica-labelled samples were genetically indistinct on a genome-wide scale. Instead, we found that Cannabis labelling was associated with variation in a small number of terpenes whose concentrations are controlled by genetic variation at tandem arrays of terpene synthase genes.
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spelling pubmed-85166492021-10-29 Cannabis labelling is associated with genetic variation in terpene synthase genes Watts, Sophie McElroy, Michel Migicovsky, Zoë Maassen, Hugo van Velzen, Robin Myles, Sean Nat Plants Brief Communication Analysis of over 100 Cannabis samples quantified for terpene and cannabinoid content and genotyped for over 100,000 single nucleotide polymorphisms indicated that Sativa- and Indica-labelled samples were genetically indistinct on a genome-wide scale. Instead, we found that Cannabis labelling was associated with variation in a small number of terpenes whose concentrations are controlled by genetic variation at tandem arrays of terpene synthase genes. Nature Publishing Group UK 2021-10-14 2021 /pmc/articles/PMC8516649/ /pubmed/34650264 http://dx.doi.org/10.1038/s41477-021-01003-y Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Brief Communication
Watts, Sophie
McElroy, Michel
Migicovsky, Zoë
Maassen, Hugo
van Velzen, Robin
Myles, Sean
Cannabis labelling is associated with genetic variation in terpene synthase genes
title Cannabis labelling is associated with genetic variation in terpene synthase genes
title_full Cannabis labelling is associated with genetic variation in terpene synthase genes
title_fullStr Cannabis labelling is associated with genetic variation in terpene synthase genes
title_full_unstemmed Cannabis labelling is associated with genetic variation in terpene synthase genes
title_short Cannabis labelling is associated with genetic variation in terpene synthase genes
title_sort cannabis labelling is associated with genetic variation in terpene synthase genes
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516649/
https://www.ncbi.nlm.nih.gov/pubmed/34650264
http://dx.doi.org/10.1038/s41477-021-01003-y
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