Cardiomyocyte Na(+) and Ca(2+) mishandling drives vicious cycle involving CaMKII, ROS, and ryanodine receptors

Cardiomyocyte Na(+) and Ca(2+) mishandling, upregulated Ca(2+)/calmodulin-dependent kinase II (CaMKII), and increased reactive oxygen species (ROS) are characteristics of various heart diseases, including heart failure (HF), long QT (LQT) syndrome, and catecholaminergic polymorphic ventricular tachy...

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Detalles Bibliográficos
Autores principales: Hegyi, Bence, Pölönen, Risto-Pekka, Hellgren, Kim T., Ko, Christopher Y., Ginsburg, Kenneth S., Bossuyt, Julie, Mercola, Mark, Bers, Donald M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516771/
https://www.ncbi.nlm.nih.gov/pubmed/34648073
http://dx.doi.org/10.1007/s00395-021-00900-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516771/
https://www.ncbi.nlm.nih.gov/pubmed/34648073
http://dx.doi.org/10.1007/s00395-021-00900-9

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