Cargando…

Potential Role and Clinical Value of PPP2CA in Hepatocellular Carcinoma

BACKGROUND AND AIMS: Protein phosphatase 2A (PP2A) is associated with many cancers. This study aimed to clarify whether PPP2CA, which encodes the alpha isoform of the catalytic subunit of PP2A, plays a role in hepatocellular carcinoma (HCC) and to identify the potential underlying molecular pathways...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Cheng-Lei, Qiu, Xue, Lin, Jin-Yan, Chen, Xiao-Yu, Zhang, Yu-Mei, Hu, Xiao-Yin, Zhong, Jian-Hong, Tang, Shen, Li, Xi-Yi, Xiang, Bang-De, Zhang, Zhi-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	XIA & HE Publishing Inc. 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516843/ https://www.ncbi.nlm.nih.gov/pubmed/34722181 http://dx.doi.org/10.14218/JCTH.2020.00168

Ejemplares similares

Comprehensive analysis of PPPCs family reveals the clinical significance of PPP1CA and PPP4C in breast cancer
por: Xie, Wenjun, et al.
Publicado: (2021)

Gankyrin and TIGAR cooperatively accelerate glucose metabolism toward the PPP and TCA cycle in hepatocellular carcinoma
por: Yang, Chun, et al.
Publicado: (2022)

Conditional Knockout in Mice Reveals the Critical Roles of Ppp2ca in Epidermis Development
por: Fang, Chao, et al.
Publicado: (2016)

Role of a Novel Functional Variant in the PPP2R1A Promoter on the Regulation of PP2A-Aalpha and the Risk of Hepatocellular Carcinoma
por: Chen, Hui-Feng, et al.
Publicado: (2013)

KIF18A interacts with PPP1CA to promote the malignant development of glioblastoma
por: Yang, Ji, et al.
Publicado: (2023)

Analysing the Zenith Tropospheric Delay Estimates in On-line Precise Point Positioning (PPP) Services and PPP Software Packages
por: Mendez Astudillo, Jorge, et al.
Publicado: (2018)

Diagnostic and prognostic value of circular RNAs in hepatocellular carcinoma
por: Sun, Jin‐Yu, et al.
Publicado: (2020)

Genetic variants in PPP2CA are associated with gastric cancer risk in a Chinese population
por: Huang, Tongtong, et al.
Publicado: (2017)

Estimating and Analyzing Long-Term Multi-GNSS Inter-System Bias Based on Uncombined PPP
por: Zhang, Fan, et al.
Publicado: (2020)

CAMTA1–PPP3CA–NFATc4 multi-protein complex mediates the resistance of colorectal cancer to oxaliplatin
por: Pan, Ruijun, et al.
Publicado: (2022)

Dietary potassium stimulates Ppp1Ca-Ppp1r1a dephosphorylation of kidney NaCl cotransporter and reduces blood pressure
por: Grimm, P. Richard, et al.
Publicado: (2023)

Arginine methylation of PPP1CA by CARM1 regulates glucose metabolism and affects osteogenic differentiation and osteoclastic differentiation
por: Zhang, Lu, et al.
Publicado: (2023)

Association between PPP2CA polymorphisms and clinical features in southwest Chinese systemic lupus erythematosus patients
por: Zhang, Junlong, et al.
Publicado: (2018)

Quantum-based modeling implies that bidentate Arg(89)-substrate binding enhances serine/threonine protein phosphatase-2A(PPP2R5D/PPP2R1A/PPP2CA)-mediated dephosphorylation
por: Salter, E. Alan, et al.
Publicado: (2023)

Improving GNSS PPP Convergence: The Case of Atmospheric-Constrained, Multi-GNSS PPP-AR
por: Aggrey, John, et al.
Publicado: (2019)

CD147 reinforces [Ca(2+)](i) oscillations and promotes oncogenic progression in hepatocellular carcinoma
por: Tang, Juan, et al.
Publicado: (2015)

TRIM72 exerts antitumor effects in breast cancer and modulates lactate production and MCT4 promoter activity by interacting with PPP3CA
por: Wang, Zheng, et al.
Publicado: (2022)

YAP ISGylation increases its stability and promotes its positive regulation on PPP by stimulating 6PGL transcription
por: Xue, Xiangfei, et al.
Publicado: (2022)

PS: 10$^{13}$ ppp
Publicado: (1975)

PPP1R26 drives hepatocellular carcinoma progression by controlling glycolysis and epithelial-mesenchymal transition
por: Yang, Yang, et al.
Publicado: (2022)

Effects of antiviral therapy on post-hepatectomy HBV reactivation and liver function in HBV DNA-negative patients with HBV-related hepatocellular carcinoma
por: Gong, Wen-Feng, et al.
Publicado: (2017)

Ionosphere-Constrained Single-Frequency PPP with an Android Smartphone and Assessment of GNSS Observations
por: Wang, Guangxing, et al.
Publicado: (2020)

PPP3R1 Promotes MSCs Senescence by Inducing Plasma Membrane Depolarization and Increasing Ca(2+) Influx
por: Li, Molin, et al.
Publicado: (2023)

Investigation of Copy Number Variations (CNVs) of the Goat PPP3CA Gene and Their Effect on Litter Size and Semen Quality
por: Bai, Yangyang, et al.
Publicado: (2022)

Comprehensive Analysis of SLC17A9 and Its Prognostic Value in Hepatocellular Carcinoma
por: Kui, Xue-Yan, et al.
Publicado: (2022)

PPP/INS Tight Integration with BDS−3 PPP−B2b Service in the Urban Environment
por: Lai, Luguang, et al.
Publicado: (2023)

Clinical and Genetic Study on a Chinese Patient with Infantile Onset Epileptic Encephalopathy carrying a PPP3CA Null Variant: a case report
por: Yang, Sai, et al.
Publicado: (2020)

Lysine methylation of PPP1CA by the methyltransferase SUV39H2 disrupts TFEB-dependent autophagy and promotes intervertebral disc degeneration
por: Liang, Huaizhen, et al.
Publicado: (2023)

The origin and radiation of the phosphoprotein phosphatase (PPP) enzymes of Eukaryotes
por: Kerk, David, et al.
Publicado: (2021)

Early-onset infant epileptic encephalopathy associated with a de novo PPP3CA gene mutation
por: Qian, Yanyan, et al.
Publicado: (2018)

On the Problem of Double-Filtering in PPP-RTK
por: Khodabandeh, A., et al.
Publicado: (2022)

Evaluation of liver regeneration and post-hepatectomy liver failure after hemihepatectomy in patients with hepatocellular carcinoma
por: Gong, Wen-Feng, et al.
Publicado: (2019)

eIF3a‐PPP2R5A‐mediated ATM/ATR dephosphorylation is essential for irinotecan‐induced DNA damage response
por: Mei, Chao, et al.
Publicado: (2022)

PPP1R81 correlates with the survival and cell proliferation in lower-grade glioma
por: Xiao, Feng, et al.
Publicado: (2023)

PPP1R3A inhibits osteogenesis and negatively regulates intracellular calcium levels in calcific tendinopathy
por: Hu, Chao, et al.
Publicado: (2023)

The Predictive Value of CA-125 and Hb for Ocular Metastasis in Hepatocellular Carcinoma Patients
por: Xiong, Xin, et al.
Publicado: (2022)

Preoperative CA19-9 and GGT ratio as a prognostic indicator in ampullary carcinoma
por: Chen, Rui-Qiu, et al.
Publicado: (2023)

Prognostic value of PD –L1 expression in patients with primary solid tumors
por: Xiang, Xiao, et al.
Publicado: (2017)

The expression profiles and prognostic values of HSP70s in hepatocellular carcinoma
por: Wang, Ben, et al.
Publicado: (2021)

The germline-enriched Ppp1r36 promotes autophagy
por: Zhang, Qinghua, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_00m2flds6rfm1ena7kp1ig6pbq