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Development of an optogenetic gene sensitive to daylight and its implications in vision restoration

Optogenetic gene-mediated therapy for restoring vision is thought to be a useful treatment for blind patients. However, light sensitivity achieved using this gene therapy is inferior to that of daylight vision. To increase light sensitivity, we designed three mutants using a bioinformatics approach....

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Detalles Bibliográficos
Autores principales: Watanabe, Yoshito, Sugano, Eriko, Tabata, Kitako, Hatakeyama, Akito, Sakajiri, Tetsuya, Fukuda, Tomokazu, Ozaki, Taku, Suzuki, Tomoya, Sayama, Tatsuki, Tomita, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516861/
https://www.ncbi.nlm.nih.gov/pubmed/34650094
http://dx.doi.org/10.1038/s41536-021-00177-5

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