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Evidence that two instead of one defective interfering RNA in influenza A virus-derived defective interfering particles (DIPs) does not enhance antiviral activity

Influenza A virus (IAV) infection constitutes a significant health threat. Defective interfering particles (DIPs) can arise during IAV infection and inhibit spread of wild type (WT) IAV. DIPs harbor defective RNA segments, termed DI RNAs, that usually contain internal deletions and interfere with re...

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Detalles Bibliográficos
Autores principales: Bdeir, Najat, Arora, Prerna, Gärtner, Sabine, Pöhlmann, Stefan, Winkler, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516915/
https://www.ncbi.nlm.nih.gov/pubmed/34650149
http://dx.doi.org/10.1038/s41598-021-99691-1

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