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GP73-mediated secretion of AFP and GP73 promotes proliferation and metastasis of hepatocellular carcinoma cells

Golgi protein 73 (GP73) and alpha fetoprotein (AFP) serve as biomarkers for the diagnosis of hepatocellular carcinoma (HCC), and their serum levels correlate with patients’ outcomes. However, the mechanisms underlying these correlations are unknown. Here we show that GP73 increased the secretion of...

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Detalles Bibliográficos
Autores principales: Liu, Yujuan, Wang, Jiyin, Yang, Ruixiang, Cheng, Yuning, Zhou, Yue, Li, Hui, Jiang, Wei, Zhang, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516944/
https://www.ncbi.nlm.nih.gov/pubmed/34650031
http://dx.doi.org/10.1038/s41389-021-00358-3