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Impaired placental mitophagy and oxidative stress are associated with dysregulated BNIP3 in preeclampsia

Preeclampsia (PE) is a severe multisystem pregnancy complication characterized by gestational hypertension and proteinuria. Bcl-2/adenovirus E1B 19-kDa interacting protein 3 (BNIP3) is a mediator of mitophagy and has been proven to be associated with PE, but the mechanism is not well understood. Thi...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaobo, Zhao, Xue, Zhou, Wei, Qi, Hongbo, Zhang, Hua, Han, Ting-li, Baker, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516954/
https://www.ncbi.nlm.nih.gov/pubmed/34650122
http://dx.doi.org/10.1038/s41598-021-99837-1

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